| 标 题: |
A Biocompatible Strain Sensor Based on Ni-GaIn and SA-Doped PAAM for Implantable Bioelectronics 基于Ni-GaIn和掺杂SA的PAAM生物相容性应变传感器用于植入式生物电子学 |
| 作 者: |
Mingxi Tu Jiawen Liang Hongji Guo Tianming Zhao Haibo Yu |
| 关键词: |
Hydrogel [水凝胶] Liquid metal [ 液态金属] Biocompatibility [ 生物相容性] Implantable [ 可植入性] Bioelectronics [ 生物电子学] |
| 出版年: |
2025 |
| 文集名: |
Intelligent Robotics and Applications 智能机器人与应用 |
| 会议名: |
17th International Conference on Intelligent Robotics and Applications (ICIRA 2024) 第17届智能机器人与应用国际会议(ICIRA 2024) |
| 届 次: |
17th |
| 摘 要: |
With the rapid evolution of sensor technology, biomaterials, and micro/nano manufacturing techniques, the performance requirements for flexible electronic devices have been increasingly elevated. These devices not only need to exhibit exceptional flexibility and stability but also require a high level of biocompatibility to adapt to a variety of application scenarios ranging from attachment to the skin surface to implantation inside the body, ultimately facilitating the monitoring and feedback of internal human body information. In this study, by doping Ni particles in Liquid metal (Ni-GaIn) to regulate the surface tension and fabricating them with a biocompatible hydrogel (SA-doped PAAM), an implantable strain sensor was successfully developed. This method not only significantly improves the processability and moldability of liquid metal by reducing its surface tension but also endows the device with excellent stretchability through the construction of a stable hydrogel-liquid metal interface. The device possesses high stretchability and can serve as an implantable stress sensor, stably sensing motion information such as bending angles within biological tissues. This research provides new insights for the design and fabrication of implantable bioelectronics and holds promising application prospects in the field of biomedical engineering.
随着传感器技术、生物材料和微/纳米制造工艺的快速发展,柔性电子器件的性能要求不断提高。这些器件不仅需要具备优异的柔韧性和稳定性,还必须具有高度的生物相容性,以适应从皮肤表面贴附到体内植入等多种应用场景,从而实现对人体内部信息的监测与反馈。本研究通过在液态金属(Ni-GaIn)中掺杂镍颗粒以调节其表面张力,并将其与生物相容性水凝胶(SA掺杂PAAM)结合制备,成功开发出一种可植入应变传感器。该方法不仅显著降低了液态金属的表面张力,从而大幅提升了其加工性和可成型性,还通过构建稳定的水凝胶-液态金属界面,赋予器件出色的拉伸性能。该器件具有高拉伸性,可作为可植入应力传感器,稳定地感知生物组织中的弯曲角度等运动信息。这项研究为可植入生物电子器件的设计与制造提供了新的见解,在生物医学工程领域具有广阔的应用前景。 |
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